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• 49Using AI to improve a challenging reaction in medicinal chemistry (openai.com)
  by ilreb7 hours ago | 5 comments
• 208The founder's playbook: Building an AI-native startup (claude.com)
  by e2e417 hours ago | 59 comments
• 117Why do commercial spaces sit vacant? (2025) (freerange.city)
  by Redoubts17 hours ago | 28 comments
• 49TREX: An AI code reviewer that runs your code (greptile.com)
  by dakshgupta9 hours ago | 5 comments
• 336AI demands more engineering discipline. Not less (charitydotwtf.substack.com)
  by BerislavLopac10 hours ago | 38 comments
• 143Abandoned and Little-Known Airfields (airfields-freeman.com)
  by wizardforhire3 days ago | 21 comments
• 9How Madrid built its metro cheaply (worksinprogress.co)
  by trymas4 hours ago | 0 comments
• 28Seventeen Camels and Where They Can Take You (mathenchant.wordpress.com)
  by ibobev2 days ago | 3 comments
• 27Bringing down my ZSH load times from ~3.1s to ~230ms (iam.mt)
  by speckx7 hours ago | 5 comments
• 185Show HN: High-Res Neural Cellular Automata (cells2pixels.github.io)
  by esychology15 hours ago | 13 comments

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