It's wild to think how long very human-like beings and modern humans existed before the technological revolution really took off. Hundreds of thousands of years of existing on the technological level of stone tools, spears, cloth made out of hides, and fire. Then at some unknown point probably in the last 100,000 years, the bow and arrow. Then about 12,000 years ago, the agricultural revolution, which probably unlocked much of the subsequent technological progress by enabling more food security and larger populations.
> Then about 12,000 years ago, the agricultural revolution, which probably unlocked much of the subsequent technological progress by enabling more food security and larger populations.
It definitely did. Also note that agriculture was invented in multiple places over time. Unfortunately, the Native Americans did not invent it quickly enough, so they had far less time for technological development before Europeans arrived. At which point, it was too late.
> Unfortunately, the Native Americans did not invent it quickly enough
This is false. Most native Americans throughout both continents—especially those in Mesoamerica—were powerful civilisations in their own right with plenty of agricultural history.
What finished many of them off was a lack of resistance to smallpox, which was brought over by the first explorers/colonists.
The lack of animals to domesticate meant fewer zoonotic diseases in Native American populations, so they were ill equipped when those diseases appeared.
IIRC, there was a massive plague in North America a decade or so before Columbus arrived.
> Harmful mutations can accumulate through inbreeding. Yet somehow Neanderthals managed to survive across most of Eurasia for nearly 400,000 years
It is also true that inbreeding for extended periods weeds out both dominant and recessive bad genes very effectively. As long as at least one good or not-so bad alternative is maintained.
So not as surprising that small groups can last a long time, once they reach a threshold, as implied by the article.
It’s a brutal way to improve the stock, as lots of individuals suffer until (and in service of) a debilitating gene going “extinct”. And every new maladaptive mutation restarts the process, but it works.
On the upside, any adaptive mutation can just as quickly become pervasive.
The biggest downside in the long term is a lack of genetic diversity as a shield against new diseases.
I wouldn't single out the concern new diseases if the population is small. Most diseases co-evolve intra-population. The lethal ones are the ones that suffer a mutation and are suddenly able to be passed to a different 'species'. So, if they already survived on a 'knife's edge', immune variety is of comparatively low concern (but still existential) on the list of things that can end your species (climate change, competition, demographics - 2-3 infertile females in a group of 20, say bye bye to tribe).
Isolated populations are all going to be creating isolated variants of any disease doing well enough to stick around.
And the impact of events where any individuals die to a new variant, is amplified for a small population. The risks of correlated vulnerability are on top of that.
Variants of the flu continue to quietly emerge and kill people today.
But you are certainly right that the cross-overs are the worst, by far.
350,000 years of just chilling, picking berries, you die in identical technological and cultural environment as when you were born. Now we got to be around when God is made in a data center
Correction: 350,000 years being riddled with parasites, fending off wild animal attacks, and avoiding being eaten alive by cannibals when your tribe runs out of food.
I know even with humans pre-modern populations were drastically smaller, but it's still just astounding to me how small of a population size it seems like Neanderthals had.
I didn’t see it mentioned in the article, but I think it’s hard to fully appreciate how at risk they were to predators and that they were certainly not the top of the food chain yet. Humans and similar aren’t naturally adept for survival in the wilderness. We developed coping mechanisms but it took some time. Had to extinct a few big cats, bears, wolfs, etc along the way.
Were they really not at the top of the food chain before modern humans came along? It's hard for me to imagine big cats and wolf packs being higher in the food chain than beings that had their own social groups, language, fire, and spears and that are known to have effectively hunted big game.
I feel like it's more to say that, "getting eaten was a legitimate concern" they weren't really the single top of the food chain because there were other animals that would reasonably consider them prey. Cave lions were massive and definitely targeted neanderthals.
Why was this the case? I thought they were at least as intelligent as modern humans and had more muscle mass, used rudimentary tools and had control over fire. They lived in a climate without a lot of dangerous animals or a lot of disease and disease vectors at least compared to the jungles of Africa.
I spent a year of high school in the Basque Country, and it always stuck out to me that a common feature of the Basques, especially the beefy ones, was incredibly caveman-like.
I know this is not unique to this population, but I also always wondered if it correlated to the fact that it is one of the historic Neanderthal populations. I have a photo of a dude I used to play soccer with that looks like I put a Neanderthal model from the natural history museum in a jersey, and I have met very few people like that in the states. The Basque Country is a very small population.
My Dad wrote an article about this 25 years ago or so: https://aoi.com.au/LB/LB705/ (How the Neanderthals became the Basques). He would really get a kick out of people reading it (he's 90 now). His website goes back to 96' and it shows.
Greetings to your father from a European with O- blood, fair freckled skin, and a receded chin! I've always been fascinated with Neanderthals. Happy to see science slowly realising these were not some stupid brutes...
This is a much-discussed topic. All we know of the Basque language is that it is pre-Indo-European.
The last time I looked in to this, the consensus was that it was most likely a version of otherwise-extinct ancient Celtic.
Now that doesn’t mean that the Basques don’t have a potentially outsized Neanderthal genetic influence, but the odds of their language being so ancient as to pre-exist modern humans entirely is unlikely.
If it has any relation to Celtic languages, then it's Indo-European by definition.
We can tell how much neanderthal ancestry someone has, more or less. Basque people have no more than others. Despite their odd language, they are much like other Europeans genetically: a similar mix of European hunter gatherers, Anatolian farmers and the bronze age invaders which we believe brought the IE languages to Europe.
It definitely did. Also note that agriculture was invented in multiple places over time. Unfortunately, the Native Americans did not invent it quickly enough, so they had far less time for technological development before Europeans arrived. At which point, it was too late.
This is false. Most native Americans throughout both continents—especially those in Mesoamerica—were powerful civilisations in their own right with plenty of agricultural history.
What finished many of them off was a lack of resistance to smallpox, which was brought over by the first explorers/colonists.
IIRC, there was a massive plague in North America a decade or so before Columbus arrived.
It is also true that inbreeding for extended periods weeds out both dominant and recessive bad genes very effectively. As long as at least one good or not-so bad alternative is maintained.
So not as surprising that small groups can last a long time, once they reach a threshold, as implied by the article.
It’s a brutal way to improve the stock, as lots of individuals suffer until (and in service of) a debilitating gene going “extinct”. And every new maladaptive mutation restarts the process, but it works.
On the upside, any adaptive mutation can just as quickly become pervasive.
The biggest downside in the long term is a lack of genetic diversity as a shield against new diseases.
And the impact of events where any individuals die to a new variant, is amplified for a small population. The risks of correlated vulnerability are on top of that.
Variants of the flu continue to quietly emerge and kill people today.
But you are certainly right that the cross-overs are the worst, by far.
I know this is not unique to this population, but I also always wondered if it correlated to the fact that it is one of the historic Neanderthal populations. I have a photo of a dude I used to play soccer with that looks like I put a Neanderthal model from the natural history museum in a jersey, and I have met very few people like that in the states. The Basque Country is a very small population.
Seems as though it could have been an enclave of neanderthals who eventually integrated with humans.
The last time I looked in to this, the consensus was that it was most likely a version of otherwise-extinct ancient Celtic.
Now that doesn’t mean that the Basques don’t have a potentially outsized Neanderthal genetic influence, but the odds of their language being so ancient as to pre-exist modern humans entirely is unlikely.
We can tell how much neanderthal ancestry someone has, more or less. Basque people have no more than others. Despite their odd language, they are much like other Europeans genetically: a similar mix of European hunter gatherers, Anatolian farmers and the bronze age invaders which we believe brought the IE languages to Europe.